Obstetrics and gynecology encompasses the vital care of women's health throughout life, from reproductive wellness and pregnancy to menopause and beyond. This dynamic field explores the complex biological processes of childbirth, the prevention of diseases affecting female reproductive organs, and the latest advancements in maternal safety. It is a discipline deeply rooted in both immediate clinical impact and long-term public health strategies.

On Gist.Science, we continuously monitor medRxiv for the newest preprints in this category, ensuring you have instant access to cutting-edge research before formal publication. Our team processes every new submission to provide both detailed technical summaries and clear, plain-language explanations, making these complex studies understandable for everyone from specialists to curious readers.

Below are the latest papers in obstetrics and gynecology, offering fresh insights into the future of women's healthcare.

📄 obstetrics and gynecology

Development and external validation of deep learning models for spontaneous preterm birth prediction from mid-trimester cervical ultrasound

This study developed and externally validated deep learning and multimodal models for predicting spontaneous preterm birth using mid-trimester cervical ultrasound, finding that while internal performance was modest, external validation yielded poor results likely due to the heterogeneity of preterm birth, suggesting a need for subtype-specific modeling and additional biomarkers.

Chanian, R., Mishra, D., Jain, R., Sharma, N., Khurana, A., Tripathi, R., Tripathi, A., group, G.-I. s., Wadhwa, N., Nob (…)2026-07-19
📄 obstetrics and gynecology

Efficacy of Gene III(R) L-Ergothioneine Capsules on Postpartum Fatigue, Sleep Quality, and Quality of Life: A Randomized, Double-Blind, Placebo-Controlled Trial

This randomized, double-blind, placebo-controlled trial demonstrates that 30 days of 120 mg/day Ergothioneine supplementation safely and significantly accelerates postpartum functional recovery, alleviating fatigue and sleep disturbances within 15 days while concurrently improving hepatic enzyme levels.

Liu, W., Guo, C., Ding, W., Cao, J., Tong, T., Zhou, S., Shao, F., Xiao, G.2026-07-18
📄 obstetrics and gynecology

Comparing measured and calculated blood loss after a caesarean birth

This secondary analysis of the I'M WOMAN trial data reveals that while measured and calculated blood loss methods show weak correlation and calculated loss overestimates high-volume thresholds, measured blood loss demonstrates superior predictive ability for severe maternal outcomes, though calculated loss remains a viable objective alternative when direct measurement is not feasible.

Mansukhani, R., Arribas, M., Bello, N., Chaudhri, R., Geer, A., Ker, K., Muganyizi, P., Prowse, D., Roberts, I.2026-07-18
📄 obstetrics and gynecology

Menstrual Cycle Changes among Reproduction-Aged Iranian Women Following COVID-19 Vaccination

This cross-sectional study of Iranian women of reproductive age found that a significant proportion experienced self-limiting menstrual cycle alterations, such as oligomenorrhea, menorrhagia, and hypomenorrhea, following COVID-19 vaccination, with prevalence rates varying by dose and highlighting the need for improved post-vaccination monitoring and counseling.

Azad, A., Darsareh, F., Ebrahimi abshur, M., Hajisafari, M., Mahmoudi Essaabadi, A.2026-07-16
📄 obstetrics and gynecology

From Christmas sex to winter intimacy: three decades of birth seasonality, sex ratio dynamics, and fertility change in South Africa, 1994-2024

This study analyzes South African birth data from 1994 to 2024 to reveal a significant shift from Christmas-season to winter conceptions, a stress-induced dip and subsequent spike in the sex ratio linked to the 2021 pandemic mortality peak, and an accelerating decline in annual fertility rates reaching a 30-year low in 2024.

Masukume, R., Chimberengwa, P. T., Masukume, G., Liczbinska, G., Grech, V., Mapanga, W.2026-07-15
📄 obstetrics and gynecology

A STUDY OF FACTORS INFLUENCING FETAL MONITOR FAILURE

This study of fetal monitors at Mongolia's Urgo Maternity Hospital identifies that device failures stem from a combination of technical issues like power instability and wear, alongside human factors such as insufficient staff training and improper use, necessitating a comprehensive approach involving regular maintenance, power stabilization, and enhanced personnel education to ensure reliable operation.

Tsanligrenchin, D., Enkhjargal, E.-U., Boldbaatar, O., Shagdar, I., Tumurtogoo, A., Tuya, A., Batbold, S.2026-07-15
📄 obstetrics and gynecology

The role of pregnancy- related comorbidities in maternal health disparities among Asian American/Pacific Islanders

This study of nearly 1.85 million California births reveals that while pregnancy-related comorbidities significantly contribute to severe maternal morbidity disparities among Asian American and Pacific Islander groups, substantial disparities persist for Filipina and Pacific Islander women even after accounting for these conditions, highlighting the need for tailored interventions beyond comorbidity management.

Dissanayake, M. V., Mathur, M. B., Main, E. K., Carmichael, S. L.2026-07-14
📄 obstetrics and gynecology

Cohort profile: the Cohort for Risk Prediction Model Evaluation (CORE) for external validation of models identifying high-risk pregnant women in the early second trimester, North India

The Cohort for Risk Prediction Model Evaluation (CORE) is a prospective, single-site Indian cohort of 964 pregnant women established to externally validate early second-trimester risk prediction models for high-risk pregnancies using harmonized clinical and ultrasound data, with the goal of improving maternal and neonatal outcomes in India and comparable settings.

Jain, R. s., Sharma, N., Khurana, A., Wadhwa, N., Tripathi, R., Jain, A., Bhatnagar, S., Thiruvengadam, R., Desiraju, B. (…)2026-07-04
📄 obstetrics and gynecology

COVID-19 containment policies and hyperglycemia in pregnancy: correlation with the Stringency Index in a nationwide Belgian cohort

In a nationwide Belgian cohort, the prevalence of hyperglycemia in pregnancy significantly increased during the latter half of 2020 compared to 2019, showing a strong positive correlation with the pandemic's Stringency Index, while neonatal weight percentiles remained unchanged.

Costa, E., Vercoutere, A., Alexander, S., Boulvain, M., Derisbourg, S., Lamy, C., Delbaere, A., Racape, J.2026-06-22